More research studies are needed to confirm the relationship between mental illnesses (MI), and increased levels of both peripheral inflammatory markers and systemic inflammation. There is a present finding indicating that the level of systemic inflammation in children with Cerebral Palsy (CP), if not treated early on, could lead to muscle contracture and muscle weakness in adults with CP. That will not only affect the physical health but also influence the development of mental health problems. Infact there are many scientists and scholars who proved that chronic inflammation is the root cause of All Chronic Diseases, and it should be addressed early on to reduce inflammation and combat all diseases!